Society for Mathematical Biology — 2017
Auto-Summary from 683 Tweets
An auto-summary generated by selecting tweets with the highest word-pair scores
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140 160 Maini: to get neural crest collective migration, models need leader and follower cell populations. Not just external signals. #smb2017
622 149 .@thillen17: classical reaction-diffusion cancer model only works if cell transport and birth are at diff., decoupled time scales #smb2017
131 147 Winfree Prize recipient, Philip Maini presents "Modeling Collective Cell Movement" #smb2017
128 127 Afternoon #smb2017 plenary lecture: Philip Maini - "Modeling Collective Cell Movement"
596 125 #smb2017 The best tweeter award winners! Paul Macklin, Courtney Davis, Joshua Bull, Keith Grant, Drew Williamson, Fergus Cooper.
377 115 Hodgkinson: Use a PDE model: flux in space, flux in structure (here a resistance axis). 5 PDEs here: cells, ECM, 2 drugs, substrate #smb2017
151 112 Maini makes a great point: when a math model is wrong, or doesn't agree with data, you learn something. Wrong is ex… https://t.co/5PBCECXn9u
130 110 Next up is Philip Maini, giving his prize talk on collective cell migration. Important in neural crest migration, angiogenesis. #smb2017
490 107 Meredith Greer: Math modeling courses are an opportunity for students to learn work happening now by diverse authors. #SMB2017
637 107 Koehl: fast velocities inside waves only lead to a slow net transport shoreward...what impact does this have on larvae in reefs? #SMB2017
170 106 Philip Maini presents work from @AlexGFletcher comparing models of epithelia. "We've become biologists; diff. answe… https://t.co/4ECCtjyJ0b
135 100 Maini - looking, via agent-based modeling, between cell attraction & repulsion. Can result in pattern development. #smb2017
175 100 When modeling, "you always have to be careful to read [and state] the conclusions based on the assumptions made." Philip Maini #SMB2017
143 97 Maini: experiments indeed validated the two-population (leaders / followers) prediction of the math models. #smb2017
504 97 .@adrianne_jenner: then models virus transmission in this framework. Dead cells need some time to shrink before releasing virus #smb2017
346 96 Day 3 of #SMB2017 opens with Marissa Baskett - "Modeling the drivers of coral response to climate change fr genes to communities." #climate
3 95 Attending #uofu Mathematical Biology Alumni Conference this weekend & #SMB2017 Exciting days of cutting edge math modeling ahead 😎👊🏻☕️☕️
172 94 @AlexGFletcher @SMB_MathBiology Enjoying great talks so far, inc Philip Maini's prize lecture about model choice wi… https://t.co/GgoJbRrZNZ
266 94 My mentee @adrianne_jenner talks this morning on modeling flu viruses as cancer treatments at 10:50 am MS16 #smb2017 https://t.co/JsDVgoV2xk
183 93 James Glazier modeling liver toxicology at the sinusoid scale in MS10 liver session (Alpine room) at #smb2017 https://t.co/Up5CIACyr6
195 93 Glazier: now starting to model flow in connected liver sinusoids built from in vivo flow imaging MS10 #SMB2017
45 92 Follow #SMB2017 this week. This is the Annual Meeting for the Society for Mathematical Biology (@SMB_MathBiology). Fantastic math bio work!
349 91 Baskett - Coral bleaching assoc with high temps often in El Nino years. Difficulty in building Ca backbone w carbonic acid. #SMB2017
659 90 Great talk by @VectorBiTE_RCN PI Leah Johnson on using math & stat models + data to tackle vector born disease like… https://t.co/lEkXS5rP0N
160 89 Maini: @ara_anderson and @mcapellanus did great work turning continuum model into discrete angiogenesis model. #smb2017
584 89 Key finding: a larger infective radius = higher peak of number of infections #SMB2017 SIR models w/spatial diffusion #maths #mathbio #math
629 89 Last plenary talk at #smb2017. Mimi Koehl. Moving trhough a turbulent environment: Embedding models in real world data.
370 88 Awesome talk by Marissa Baskett on modeling resistant and resilient coral systems' coexistence in the face of clima… https://t.co/p3x3zGPTSk
292 87 My question for .@adrianne_jenner: model assumes constant rate of virus replication. Can the rate vary? (e.g., infected by 2 virii) #smb2017
436 87 4 @UUtah Students receiving poster awards at @smb2017 + Prof. Jim 'kdawg' Keener winning the Education Prize. Utah #mathbio 👏🏼🏆💁🏻#SMB2017
76 85 .@mcapellanus: Shows work with D. Schlatterer on agent-based models of cell migration in ECM fibers. Cells realign fibers. #smb2017
641 85 Koehl: Hawaiian flow experiment Large yellow dye relase. Group of scientists onshore. tourist boat goes by #smb2017
317 84 @ Alpine Room, Guest House; Heidi Dritschel modelling cancer induced T-cell exhaustion #SMB2017
147 83 "Using experiments in a chick to mimic a human is ~ as abstract as using a math model to mimic a human. We are all modelers." Maini #SMB2017
597 83 Shahriyari: chronic inflammation could lead to immune cell adaptation, causing higher levels of proliferative signalling #SMB2017
186 82 James Glazier - Acetaminophen has a very low effectiv e-dose to fatal-dose ration.Liely would be banned apart fr political reasons. #smb2017
362 82 Baskett: Two species model - more resistant coral vs more resilient coral (growth & recruit) vs macro-algae. #smb2017
599 82 Shahriyari: says that chronic inflammation can eventually adapt distant primary cells to down-reg TSGs, grow as new "mets" #smb2017
168 81 Maini work with @AlexGFletcher et al: major problem that many models of same epithelial sheets can give very different results. #smb2017
414 81 John Nagy shows how his multi-scale model can help predict castration resistance in prostate cancer. #SMB2017 https://t.co/JyuwxPxzvl
275 80 Kim: GBM recurs, and large part is due to cell migration within the brain. Looks at role of tumor microenvironment (TME) in this. #smb2017
647 80 Baratchart: Build a model of macrophage plasticity in homeostasis, then add cancer dynamics after this #SMB2017
293 79 .@adrianne_jenner: Now, uses models to analyze experiments that remove viral proteins, look at impact on virus efficacy #smb2017
334 79 Congratulations to @WCMBlog's own Philip Maini on receiving the Winfree Prize from @SMB_MathBiology at #SMB2017. A well-deserved honor!
121 77 Metzcar - coupling environment model with a tumor moddel. Cell movement, growtth, and death. #smb2017
285 77 .@adrianne_jenner: Can a genetically engineered virus be used to fight cancer? starts w viral replication process. #smb2017
132 76 Maini: Math models can show what's impossible, what could happen, but experiments can verify which of those does happen. #smb2017
139 76 Great talk by Philip Maini on collective cell migration at the SMB annual meeting #SMB2017 #Utah @JenniferOwen123 https://t.co/tMzRNfYAAH
141 76 Maini - Diffusion didn't work. Neither did VEGF as a chemical attractant. Leader/Follower (2 types) more promising. #SMB2017
252 75 #smb2017 day 2 kicks off with plenary talk by Atsushi Mochizuki, insights into complex systems based on dynamic network structure
278 75 Kim discusses the crucial role of tumor microenvironment in altering macrophage phenotype - some great work on this at #smb2017 this year!
375 75 Arran Hodgkinson in CS9: developing a spatial, phenotype-structured model of resistance. Improvement over discrete states. #smb2017
298 74 Next up is Khaphetsi Joseph Mahasa on modeling oncolytic potency, reduced viral tumor specificity in virotherapy. #smb2017
401 74 Judy Day's model of pathogen / pro-inflammation / damage / anti-inflammation (ODE system) can show healthy & aseptic death outcomes #smb2017
435 74 Jim Keener received John Jungck Award for Excellence in Education. Absolutely deserving. He changed our lives. Go,… https://t.co/XUjBWPb3Vo
255 73 Atsushi Mochizuki kicks off Tuesday's programme with his plenary talk on modelling complex networks #SMB2017
446 73 Finley: non-spatial compartment model (tissue) with 130 ODE's. Sampling of parameter distributions to gain output distribution. #smb2017
228 72 Mumenthaler shows automated high throughput system for image recognition involving machine learning classifiers - cool stuff! #SMB2017
389 72 Susan Massey takes to the stage here in the City Creek Cancer session now, with a model of proneural gliomas #smb2017
654 72 Baratchart: estimates parameters for homeostasis; uses ODE modelling to test hypotheses regarding monocyte differentiation into MPs #SMB2017
149 71 Great to see Philip Maini explain the work of my former office mate @LinusSchumacher in his Winfree prize talk at #SMB2017
150 71 #SMB2017 "All models are wrong but wrong models is when you learn!"- Philip Maini #truth
152 71 "Nearly all models are wrong. And when they're wrong is when it's fun!" Philip Maini #SMB2017
270 71 I'm in MS16 this morning. First up is Yangjin Kim, on his cancer modeling work. Much of it with Hans Othmer. #smb2017
176 70 Packed house for Winfree prize winner Prof Philip Maini @OxUniMaths #SMB2017 @SantiagoSchnell introducing https://t.co/Zq9hF7bXtP
32 69 I will speak on cm^2 agent-based models of liver metastases using #PhysiCell. #SMB2017 4/7 MS10 on Mon. afternoon https://t.co/inFpxbLbJ5
146 69 Maini - It's more exciting when your model doesn't agree with experiment ; It means there's more to learn. #smb2017
158 69 Maini: old work by McElwain (1985) Leah Edelstein (1982) had PDEs for tip, sprout cells, and phenotype switching. #smb2017
161 69 Maini: BUT, turning discrete back into PDE model doesn't match. Leads to new models. #smb2017
570 69 Leah Johnson: Combining tactical and strattegic approaches to predict vector-borne diseases. #smb2017
572 69 Next up: Leah Johnson on "Combining tactical & strategic approaches to predict vector-borne disease" #SMB2017… https://t.co/GpPRWK4rey
107 68 @DIYOzzy begins the first talk featuring @Chaste_Project at #SMB2017 with his work on multicellular modelling of colorectal cancer
613 68 Walker: local treatment can induce rapid non-local outgrowth. And radiation therapy can change state of non-local mets. #smb2017
621 68 Closing out #SMB2017 with my talk "Optimal fishery harvesting modeling the effects of habitat degradation." today at 4:45, City Creek Room.
640 68 Koehl: shows PLIF images (Planar laser induced fluorescence) showing a 1mm slice through a cloud of dye - really cool imaging! #SMB2017
290 67 .@adrianne_jenner: shows a nice system of ODEs (with the prob distributions) for number of cells replicating virus, etc. #smb2017
505 67 .@adrianne_jenner: Nice finding, increase virus dosage, don't get better response. Unlike ODE systems, it's not well-mixed! #smb2017
67 66 .@mcapellanus: Kobayashi (not Maru) not just a training scenario to wreak havoc on Star Fleet cadets. Great Hes1 data source. :-) #smb2017
190 66 Glacier perturbs a reference simulation to model Tylenol metabolism in a pop of 1000 virtual patients. Outliers eme… https://t.co/mfdIzkloP0
118 65 John Metzcar - The role of hypoxia in tumor development. Main focus on breast cancer. #smb2017
181 65 Macklin - Liver cells are mechano-sensitive. Flow can affect phenotype. Perfusion affects organized tissue or "liverwurst". #smb2017
546 64 Plenary talk for last morning of #smb2017. Jonathan Dushoff, "Epedemic strength and speed: rethinking metrics for disease spread & control"
561 64 #SMB2017 mini symposium on "Confronting models w/ data" starting now with Juan Gutierrez @smb2017 https://t.co/z6PopLRt8o
619 64 The final talk of the session comes from @thillen17, on the use of non-local birth-jump processes to model cancer spread #smb2017
638 64 Koehl: "Large organism chauvinist pigs" look at flow at large scale - we need to consider flow on the scale of microscopic larvae! #SMB2017
57 63 @mcapellanus kicks off #SMB2017 with a plenary talk on modelling cancer at multiple scales
361 63 Marissa Baskett illustrates the tension between resistant and resilient populations in surviving environmental chan… https://t.co/cxztq168mS
271 62 Kim: Working on glioblastoma multiforme (GBM), an aggressive brain cancer well known to @gliomath and @rrockne. ~1 yr survival time #smb2017
393 62 Susan Massey showing a PDE model for PDGF driven GBM. #abbvs Part of her PhD work with @gliomath #SMB2017 https://t.co/6l42LdKvm0
402 62 In Day's model, "aseptic death" is where pathogen is eliminated, but inflammation and tissue damage grow. #smb2017
116 61 ...aaand a dash outside to the Officer's Club for John Burke on clinical uses of modelling. Utah is seriously, seriously hot! #smb2017
254 61 Mochizuki - Studying biological network dynamics. #SMB2017 Structural theories. Linkage logic, rate constants.
363 61 Baskett: Resilient coral - faster growth and greater basin of attraction vs macro-algae. #smb2017
462 61 First talk, Gary An "High-Performance computing-augmented use and analysis of Agent-based Models.. new math for biology." #SMB2017
463 61 #SMB2017 heterogeneity in disease transm session is on! my invited talk is on weekend/holiday's impact on flu spread, work w/ @HensNiel lab
590 61 Lowengrub: nondimensional analysis of a mechanistic model gives new image analysis biomarkers for PDAC. Complements molec markers #smb2017
81 60 .@mcapellanus kicks off #SMB2017 with models at all scales of cancer growth and development https://t.co/cY8hgzQcVQ
122 60 John Metzcar of the @MathCancer lab at @IUBloomington is currently showing model of the effect of hypoxia during tumor metastasis #SMB2017
268 60 Session on Data Science at #smb2017 leads off with Lindsay Keegan "Using correlated provinces to Predict Dengue incidence in Thailand".
417 60 .@NaraYoon12: how can we choose the order of multiple drug treatments to avoid resistance? Highly clinically relevant question! #smb2017
483 60 honored to receive Leah Edelstein-Keshet prize from @SMB_MathBiology and give an award talk in front of amazing math biologists! #smb2017
501 60 .@adrianne_jenner: Works with a Voronoi cell-based model. Delaunay triangulation helps you find neighbors. #smb2017
634 60 last plenary session by Mimi Koehl from @UCBerkeley - movement of microscopic organisms in real-world (turbulent) environments #smb2017
642 60 Koehl Slug larvae flow passively with water flow but sink in response to coral scent #smb2017
227 59 Mumenthaler: integrating machine learning with the microscopy platform for automatic cell segmentation and identification. Neat! #smb2017
250 59 Inmunobiology & Infection Subgroup mixer at lunch today. 12:30pm in Officers Club West. #SMB2017
354 59 Baskett: Calculate population growth factor as f(phenotype). Add evolution of phenotype as climate response. #smb2017
555 59 "Generation times look shorter at beginning of an epidemic." Jonathan Dushoff #SMB2017 Is this corrected when modeling real-time outbreaks?
52 58 Mark Chaplain (@mcapellanus) now kicking off his plenary. Will speak about multiscale modeling of cancer. #smb2017
72 58 .@mcapellanus moves up a scale from gene transcription dynamics to focus on individual-based, force-based models of tumour growth #smb2017
366 58 Marissa Baskett: "Competitor-enabled rescue effect & enhanced community resilience in coral": coral are stronger together. #SMB2017
496 58 Gevertz: problem for original "optimal" treatment, based on data that turned out to be close to a bifurcation point! #smb2017
222 57 Mumenthaler: many biomemetic models available now to study cancer. A range of complexity, cost, realism. #smb2017
316 57 Last talk: Evans Afenya (@ElmhurstCollege) on math modeling in cancer prevention and treatment #smb2017
558 57 At session M33 of #smb2017 : Confronting biological models with data : dealing with complexity & sparsity 1.
620 57 Last talk this morning is @thillen17! On modeling cancer spread with non-local birth-jump processes. #smb2017
154 56 Now Maini moves on to angiogenesis modeling with Helen Byrne and Samara Pallay. #smb2017
167 56 Maini - Running different models on cell sorting due to different adhesions. #smb2017
369 56 Conclusions from M. Baskett @smb2017 We rely on the power of parameters + sensitivity analysis for management when data is limited #SMB2017
381 56 Hodgkinson: fate of tumour is dependent on degree of heterogeneity at start of treatment - more heterogeneity implies resistance! #smb2017
595 56 Shahriyari: May be that not all metastases arise from circulating tumor cells (CTCs). Now discussing chronic inflammation. #smb2017
615 56 Walker calls out @JPoleszczuk for critical work calculating blood flow, estimating which T-cells arrive at each site in metastasis #smb2017
5 55 To save #SMB2017 folks the look-up: At airport, light rail (TRAX) at Terminal 1 end. Transfer Courthouse. Red to U.… https://t.co/07DP8Z1ZqW
54 55 "modeling cancer at multiple scales" by @mcapellanus, wonderful way to start off #smb2017
77 55 .@mcapellanus agent-based model: stiffness and alignment both important for cell motion in interactions with matrix #SMB2017
156 55 Maini: using a very old "snail trail" conceptual model, was also a leader-follower type of phenomenon. #smb2017
166 55 ChasteWatch 2017: Maini discusses comparison of models with @DIYOzzy, @AlexGFletcher, Gavaghan, Pitt-Francis @Chaste_Project #SMB2017
245 55 Developmental biology subgroup mixer at lunch today: Commanders Office Den. Hope to see you there! #SMB2017
448 55 @USCSysBio_Lab: math model can explain why some heavily-pursued TSP1 mimetics don't pan out in trials. #smb2017
500 55 Next up: @adrianne_jenner (my SMB mentee!) on impact of tumor pressure on outcome of cancer treatments. #smb2017
627 55 @thillen17: Birth-jump models form new class of non-local continuum models. Open Q: how do they act in spatially explicit contexts? #smb2017
65 54 .@mcapellanus: prior models (2-ODEs): no oscillations in well-mixed ODE models. Need to introduce delays to match real world. #smb2017
113 54 Raluca Eftimie highlights the need for data distinguishing between M1 and M2 macrophages to tune models of oncolyti… https://t.co/zuG2SdDmpB
459 54 @USCSysBio_Lab: most predictive anti-VEGF response marker is a parameter describing exponential-to-logistic growth transition. #smb2017
666 54 #SMB2017: Final speaker of "Confronting Biological Models with Data" is Dean Koch @smb2017 https://t.co/Oza3w4D4PV
11 53 @EnderlingLab will be represented at #SMB2017 by @santiadn (oncolytic virus), Rachel Walker (systemic immunity) & Tom Lewin (radiotherapy)
134 53 Maini - Cells don't stay put, they move to where they will function. Understanding normal development can help w cancer. #smb2017
17 52 Missing #SMB2017 this year. Wishing lots of fun and exciting science to all @SMB_MathBiology friends and colleagues at @UUtah this year
101 52 Athens - A discrete stochastic model to simulate the multistep transformation to cancer. #SMB2017
396 52 Susan Massey's model shows the importance of early treatment of gliomas with non-competitive PDGF-inhibitors > comp… https://t.co/v4pYDv6DN3
413 52 Nagy: evolution vs plasticity isn't enough - to understand resistance, must investigate evolution of cells with a plastic phenotype #smb2017
559 52 First session talk: Juan Gutierrez - "Modeling across scales: From data sparsity to data overload." #smb2017
133 51 Maini: notes that neural crest work is with @ruth_baker, Kay, McLennan, Dyson, @LinusSchumacher. #smb2017
202 51 Omar Saucedo from @mbi_osu combines graph theory and dynamical systems to model Zika transmission. #SMB2017 https://t.co/sD3ay40P2d
364 51 Baskett: Synergy between two coral types in holding off macro-algae. "competitor enabled rescue effect". #smb2017
442 51 Time for the first ever Leah Edelstein-Keshet prize talk, the plenary session from @USCSysBio_Lab on angiogenesis in breast cancer #SMB2017
455 51 Finley: Can we use the model with only data before any drug is given to predict response to treatment? #smb2017
679 51 Stay tuned for some #SMB2017 tweets too! There were many wonderful talks, but our (main) webmaster stuck to SI, SIR & SEIR models! 😉
4 50 Onward to *UT Math Bio reunion *#SMB2017 *SURB final week (while away) *#MathFest2017 It's going to be a great couple of weeks in math bio!
39 50 @iusoic We have space and rolling admissions for great students in the bio track, w heavy computational modeling component! (2/3) #smb2017
74 50 Delighted to encounter hes1oscillations in Mark Chaplains opening talk at #SMB2017 @PapalopuluLab - delays emerge from spatial interactions
96 50 Chaplain (earlier) - Spatial movement of molecules important to oscillations without adding delay. Then add stochasticity. #smb2017
163 50 Maini: mean-field assumption seems to be where much discrete-continuum model matching seems to break down. #smb2017
295 50 A nice presentation by @adrianne_jenner on using flu viruses to treat tumors - and ending with a plug for @SMB2018!!! #SMB2017
347 50 We're changing gears for this morning's plenary session here at #smb2017 - Marissa Baskett starts the day with ecological modelling
380 50 Mark Alber starts by discussing the challenges of modelling multicellular tissue development. #smb2017 https://t.co/8qqgVQhJcu
390 50 .@mathematista avoids knockout models because they often don't just knock out *one* thing. Instead varies level/time of coinfection #smb2017
502 50 .@adrianne_jenner: Does a nice job of using Hooke's law to generate a pressure that moves cells around. #smb2017
563 50 Hannan: what is the impact of surgery on breast cancer metastasis? Presents data from cohort of 673 patients treated by surgery #SMB2017
652 50 "Save a newt; eat a crayfish!" City Creek Room at 3:45-4 in the Ecological Dynamics section. #SMB2017 https://t.co/ABdbMcbeRy